Invokana and Risk of Ketoacidosis
Kentucky has one of the highest populations of diabetics in the country. In 2013, 10.6% of the population of Kentucky was diagnosed with diabetes, as compared to the national average of 9.7%. Diabetes is the 7th leading cause of death in Kentucky. With numbers like these it is no wonder that the market for diabetes drugs is at an all-time high. One of the fastest growing diabetes medication is Invokana, manufactured by Johnson & Johnson. Invokana was introduced in 2013 and it is trending to have over $1 billion in sales in 2015. However, the FDA has recently issued a warning that Invoka and similar diabetes drugs may cause ketoacidosis, a condition where the body produces high levels of blood acids that can have serious health consequences. Further studies and investigations are currently underway.
What is Invokana?
Invokana is one of a new class of Type II diabetes drugs called Sodium-Glucose Costransporter-2 (SGLT-2) inhibitors. SGLT-2 Inhibitors work by altering the normal kidney function so that less sugar is reabsorbed into the blood and the surplus glucose is excreted through the urine. The active ingredient in Invokana is canagliflozin.
Side Effects of Invokana
The FDA warning on Invokana came after the agency’s database identified 20 cases of acidosis that required hospitalization in the first 14 months of Invokana’s introduction. Additionally, there were over 450 additional adverse events reported for Invokana in its first year on the market. The serious side effects linked to Invokana include:
- Kidney failure
- Kidney stones
- Kidney damage
- Urinary tract infections
- Fluid/electrolyte problems
- Weight loss
What are the Symptoms of Ketoacidosis?
Patients using Invokana should be alert as to the symptoms of ketoacidosis which include:
- Difficulty breathing
- Abdominal pain
- Unusual fatigue
Patients should report such symptoms to their medical provider. Patients should not discontinue use of Invokana without speaking to a physician.
Invokana Lawsuits in Kentucky
Kentucky patients who have developed ketoacidosis since beginning Type 2 Diabetes treatment with Invokana may want to explore their legal options. Currently there are a number of lawyers exploring lawsuits against Johnson& Johnson, the maker of Invokana, alleging that the pharmaceutical company did not adequately warn users of the risks of ketoacidosis. An attorney can help you to determine if your case warrants investigation. Please contact Brett H. Oppenheimer, a Kentucky lawyer, who can review your case. Call 502-242-8877 for a free consultation.